Many drugs in the treatment of cancer pain treatment method can be applied to the operation available. Treatment, the type and severity of pain, and the risk factors contained in the treatment varies from patient to patient according to individual preferences. The main drugs used for cancer pain in opioid-derived analgesics.However, these drugs are at risk of developing dependence and tolerance to the drug. Cancer patients are often due to various reasons, can not receive treatment. The most common treatment method is as follows:
sedative
Non-opioid analgesics
Derivative opioid pain relievers
auxiliary agents
The World Health Organization (WHO) -line treatment system
psychotherapy
interventional procedure
Exercise and massage
behavioral methods to control pain
sedative
pain medication to relieve pain in most patients the main method to disconnect. 70 to 90% of cancer patients with non-opioid analgesics, opioid pain relievers and various combinations of drugs to help treat pain according to the WHO-line treatment can provided. Painkillers cause pain, which is not a cure, provide temporary relief.
Non-opioid analgesics
Aspirin for mild pain, paracetamol or ibuprofen can be used as a simple analgesic. Aspirin and ibuprofen pain of non-steroidal structure. There is a ceiling effect this drugs. So after a certain dose of the drug to be more visible increase in influence. Develop drugs against this type of habit or addiction. Studies just as much as 20-40% of patients with pain relief painful non-opioid pain has passed. Patients, the response to these drugs varies, and which patients will respond to which drugs can be found in the experiment.
Derivative opioid pain relievers
Prototype types of opioid painkillers morphine. However, the efficacy and side effects of opioid drugs changed much. Unlike painkillers non-opioid, there is no ceiling effect of opioid drugs. the effect increased with increasing doses of pain until unconsciousness develops. Opioids used for severe pain. Opioid drugs have the potential for addiction. Opioid drug dependence, many doctors fear severe pain in patients with unremitting pain and other medications are prescribed, even Avoid. proper handling pain in patients with cancer pain is one of the most important reasons. However, studies in patients with opioid addiction to the drug proved to be a very low risk.
opioid, fentanyl can be used through the skin. Fentanyl-impregnated strips attached to the skin and the drug is absorbed through the skin into the blood in this way. non-opioid analgesics, opioid-acetaminophen combinations, such as not responding to other pain medications are used to treat moderate pain and severe chronic pain relief for 72 hours to cut. Change and continuity of care is given at the end of 72 hours of recording.
Band is available in a range of doses of fentanyl. Therefore, the dose can be adjusted individually. acute pain and postoperative analgesic efficacy of the resulting tapes are not suitable for pain. Also not be used in children under the age of 2 years.
Fentanyl bands can interfere with breathing. repeated applications may develop tolerance and habits. Other side effects are as follows:
Confusion
Constipation
dry mouth
The tendency to fall asleep
increased sweating
Increased blood pressure (hypertension) or decrease (hypotension)
Nausea and vomiting
developed tolerance to opioids in patients with the addition of a sudden and intermittent opioids used for breakthrough pain. The goal is to pass quickly, while providing a pain to avoid side effects is to use a short-acting drug. The additional opioids given by mouth in the form of a tablet, or suppository can be shaped in the form of lozenges under the tongue may be involved in the blood. oral opioid that is used is the most suitable and cheapest, but the effects of a given drug in this manner may be due to begin Moreover late.In, while too much medicine is left in the blood stream, which dizziness, drowsiness and may cause side effects such as vomiting.
Studies have shown that morphine under the tongue, use of the drug in the blood slows down. This is a rule of the road has been determined that oral use.
Participates in opioid fentanyl across the oral mucosa in the blood in patients with advanced resistance to be used for breakthrough pain. It is used as a tablet. The effect of opioid drugs are used as a wick starts fast, but many patients do not want to use the drug in this way.
Pain in cancer patients given oral opioids or by absorption through the skin of opioid analgesics when they are not enough to cut the spinal canal, called a probe inserted through the catheter directly to the nerves pain transmission method given. This also be called morphine pump. Catheter inserted into a drug combination consisting of opioid analgesics and anesthetics local occur. Thus, pain, cancer pain in patients with low doses of oral drug with a drug can be cut more. The drug is also involved in the systemic circulation would be part of the very low frequency and severity of the side effects of opioid drugs is reduced.
auxiliaries
auxiliary agents such as neuropathic pain and bone pain, type of pain relief drugs pain to increase the impact occur. Type of opioid analgesics or other non-opioid analgesics for neuropathic pain responds to the pain. Supporting other drugs are also used to reduce the side effects of analgesics. Always the first choice drugs for relief of pain in neuropathic pain, neuropathic pain, but usually do not respond well to conventional medications for pain relief. Antidepressants (depression medications), anticonvulsants (epilepsy drugs), oral local anesthetics, such as cortisone-type drugs drugs used to treat neuropathic pain help. For this purpose, the doses are much lower than the doses in the treatment of depression.
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